Mounjaro Weight Loss

Like Wegovy, Mounjaro is an injectable medication that regulates blood sugar weekly. Currently, Mounjarno is approved for those with type 2 diabetes, but there is also evidence to show that it can be used as a medication for Mounjaro weight loss too. 

Clinical trials showed that the active ingredient in Mounjaro, tirzepatide, effectively lowered hemaglobin A1C and contributed to weight loss. Preliminary data even showed that Mounjaro can reduce the chances of stroke or even heart attack. 

While Mounjaro seems promising for those looking to lose weight, it should be combined with self-improvement changes like a cleaner diet and more frequent workouts. 

Doctors recommend taking 2.5mg of Mounjaro when you start and then increasing the dosage after four weeks to a maximum of 15 mg weekly. Doctors will set and monitor a patient’s dosage based on the patient’s needs.

What is Mounjaro?

Mounjaro is a new drug developed by Merck, a leading pharmaceutical company, for treating obesity and type 2 diabetes. Mounjaro combines two drugs, a GLP-1 receptor agonist and a glucagon receptor antagonist, to regulate glucose metabolism and promote weight loss.

Is Mounjaro approved for weight loss?

Mounjaro is not currently approved for weight loss, but was originally developed by Merck to treat obesity and type 2 diabetes. Researchers are in the early stages of developing Mounjarno, and its safety and efficacy have yet to be established. The public needs more clinical trials to determine its potential as a treatment option for obesity and type 2 diabetes. It would be the first long-acting GLP-1 receptor agonist to be marketed for these conditions if approved.

How does Mounjaro work?

A GLP-1 receptor agonist mimics the effects of GLP-1, a hormone that regulates glucose metabolism and makes us feel full, which can result in decreased food intake and weight loss. On the other hand, glucagon receptor antagonists inhibit the production of glucagon, which increases glucose production and leads to high blood sugar levels in diabetics.

Mounjaro marries the effects of both drugs to provide a more streamlined approach for treating obesity and type 2 diabetes. In preclinical studies, Mounjaro was shown to be helpful in losing weight, improving glycemic control and reducing cardiometabolic risk markers. People with these conditions may find Mounjaro an effective and convenient treatment option.

Mounjaro works like other medications in the GLP-1 family, but it also has an additional molecule that gives it an advantage over its GLP brethren. If you’re wondering what is Mounjaro, the drug’s action design imitates both hormones controlling blood sugar, GLP-1 and GIP.

Why mimic incretin hormones?

By increasing insulin production in the pancreas and suppressing glucagon production, increasing hormones delay gastric emptying and activate the brain’s satiety centers. 

Since incretin hormones and their imitators are glucose-dependent, they are unlikely to cause serious hypoglycemia.

Those suffering from obesity and overweight may have low levels of natural incretin hormones, especially if they diet frequently. GLP-1-type medications help you achieve your weight loss goals and lower your metabolic rate.

Mounjaro interactions and warnings

If you’re wondering how does Mounjaro work, know that it is not without its side effects, including nausea, indigestion, stomach pain, constipation and diarrhea. There are even more severe side effects which include thyroid cancer. If you’re wondering how does Mounjaro work for weight loss, you must assess whether the benefits are reasonably worth the risks. 

Mounjaro can also cause pancreatitis, which causes severe stomach and abdominal pain. Finally, Mounjaro can cause gallbladder problems and even kidney failure.

How good is Mounjaro for weight loss?

Like other GLP-1 medications, Mounjaro makes patients feel less hungry and thus eat less food. This medication is beneficial for people who struggle to manage their hunger cravings and end up overeating. 

By acting on GIP receptors, Mounjaro has an advantage over other GLP-1 receptor antagonists, like Semaglutide, to curb hunger pangs. This is because blood sugar rises after a meal, and GIP encourages the pancreas to release insulin. Then, when the blood sugar levels decrease, GIP commands the pancreas to release glucagon instead of insulin. Therefore, because insulin reduces blood sugar while glucagon increases blood sugar, GIP is an important hormone for regulating blood sugar levels. 

Controlling these methods can prevent a blood sugar crash that leads to cravings like donuts or candy. Some research points to GIP increasing energy expenditure, an additional perk for people trying to lose weight.

Mounjaro for weight loss: Key takeaways

Mounjaro may be the hottest, sexiest new weight loss drug, but it’s essential to check the figures and results of a drug to know that you’re not just buying snake oil. Here’s what you should know about Mounjaro:

• Mounjaro is both a GIP and GLP-1 receptor, working on both simultaneously! This is one of the most significant differences between Mounjaro vs. Ozempic, which only acts on GLP-1 receptors.
• In May 2022, Mounjaro was FDA-approved for those with type-2 diabetes. It’s not yet approved for weight loss, but there is some evidence that Mounjaro is a treatment for weight loss.
• The SURPASS-2 clinical trial of Mounjaro showed A1C reductions averaged up to 2.3 percent versus their baseline. The trial also showed that Mounjaro, Mounjaro’s active ingredient, produced 5.5 kg more in weight lost when measured next to semaglutide.
• Mounjaro is currently available nationwide in pharmacies everywhere, however since its only been distributed since June 2022, availability may be limited.
• Calibrate doctors are now prescribing Mounjaro where appropriate. Depending on your unique health history and profile, you may be prescribed a different type of drug.

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